Name :
MAPKAPK3 (Human) Recombinant Protein
Biological Activity :
Human MAPKAPK3 (NP_004626.1, 1 a.a. – 382 a.a.) full length recombinant protein with GST-tag at N-terminal using baculovirus expression system.Bioactive Protein,Bioactive Proteins,Bioactive,Active,Functional Protein,Functional Proteins,Full-Length Protein,Full-Length Proteins,Full-Length,Full Length,FullLength
Tag :
Result of activity analysis
Protein Accession No. :
NP_004626.1
Protein Accession No.URL :
https://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=7867
Amino Acid Sequence :
Molecular Weight :
Storage and Stability :
Stored at -80°C.Aliquot to avoid repeated freezing and thawing.
Host :
Viruses
Interspecies Antigen Sequence :
Preparation Method :
Baculovirus expression system.
Purification :
Glutathione sepharose chromatography and Ni-NTA affinity chromatography.
Quality Control Testing :
The purity was assessed by SDS-PAGE/CBB staining.
Storage Buffer :
50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
Applications :
Functional Study，
Gene Name :
MAPKAPK3
Gene Alias :
3PK, MAPKAP3
Gene Description :
mitogen-activated protein kinase-activated protein kinase 3
Gene Summary :
This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. [provided by RefSeq
Other Designations :
MAPKAP kinase 3
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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