Name :
Recombinant Mouse PLGF/PGF Protein
Biological Activity :
Background :
Biological Activity :
Measured by its binding ability in a functional ELISA. Immobilized mouse PGF at 10 μg/mL (100ul/well) can bind human VEGFR1-His (Cat:10136-H08H). The EC50 of human VEGFR1-His (Cat:10136-H08H) is 0.07-0.15 μg/mL.
Expression Host :
Mouse
Source :
HEK293 Cells
Tag :
Protein Accession No. :
P49764
NCBI Gene ID :
Synonyms :
Synonyms :
placental growth factor
Amino Acid Sequence :
Molecular Weight :
The recombinant mouse PGF consists of 146 amino acids and has a calculated molecular mass of 16.6 kDa. The recombinant protein migrates as an approximately 28 kDa band in SDS-PAGE under reducing conditions.
Purity :
> 90 % as determined by SDS-PAGE
State of Matter :
Product Concentration :
Storage and Stability :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Endotoxin Level :
< 1.0 EU per μg of the protein as determined by the LAL method
Protein Construction :
A DNA sequence encoding the mouse PGF (P49764) (Met1-Pro158) was fused with five amino acids (DDDDK) at the C-terminus was expressed and purified.
Buffer Solution :
Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet.
Shipping :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Redissolution :
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Synonyms :
AI854365 Protein, Mouse; PIGF Protein, Mouse; Plgf Protein, Mouse PLGF/PGF 背景信息
References & Citations :
Nagy JA, et al. (2003) VEGF-A(164/165) and PLGF: roles in angiogenesis and arteriogenesis. Trends Cardiovasc Med. 13(5): 169-75.Chaballe L, et al. (2011) Placental growth factor: a tissue modelling factor with therapeutic potentials in neurology? Acta Neurol Belg. 111(1): 10-7.Odorisio T, et al. (2006) The placental growth factor in skin angiogenesis. J Dermatol Sci. 41(1): 11-9.
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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