Daily Archives: December 15, 2016

We reported the generation of cell lines that preserve the entire promoter regulator networks controlling SNCA expression for HTS of small compounds that alter the interactions of the distal elements with the SNCA promoter

We described the era of mobile lines that preserve the complete promoter regulator networks managing SNCA expression for HTS of tiny compounds that alter the interactions of the distal elements with the SNCA promoter. Because of the complexity of SNCA expression control and great duration of the SNCA promoter, we employed genome editing to introduce…

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