The presence or absence of HORMAD1/2 and phosphorylation of HORMAD1 and SMC3. At unsynapsed chromosomal regions, the chromosome axis contains the S/T-Q motif-phosphorylated forms of HORMAD1/2 and SMC3. When homologs…
June 2021
Ation of ATM and DNA repair pathways. In contrast, adenoviruses induce the degradation of DDR proteins like p53, BLM, and Mre11, leading towards the repression of DDR and of apoptosis.…
Crb2D cut5-crb2(675)-2AQ cells behaved exactly like crb2D in that no Chk1 foci were detected along with the cells failed to arrest in response to DNA damage (Figure 6A). Inside a…
Lization of Cdc25.Accepted 24 March, 2014. For correspondence. E-mail [email protected]; Tel. (+46) 31 786 3830; Fax (+46) 31 786 3801.2014 The Authors. Molecular Microbiology published by John Wiley Sons Ltd.…
Ells expressing truncated types of Crb2, Crb2(158)-LZ or Crb2(27678). Crb2(158)-LZ, which lacks the histone-binding Tudor domains and BRCT domains, but is supplemented with a heterologous leucine zipper (LZ) dimerization motif,…