Daily Archives: February 9, 2017

In the cerebellar cultures stimulated with LPS, we observed ROS production and iNOS expression in activated microglia indicating induction of oxidative stress

In the cerebellar cultures stimulated with LPS, we noticed ROS manufacturing and iNOS expression in activated microglia indicating induction of oxidative tension. LPS activates microglia and astrocytes by binding to TLR4, marketing the induction of iNOS, which in flip creates ROS [28]. Activation of microglia and astrocytes occurs at diverse stage in many neurodegenerative conditions….

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