Product Name :
Ac-CoA Synthase Inhibitor1
Description:
Ac-CoA Synthase Inhibitor1 is a potent, reversible acetate-dependent acetyl-CoA synthetase 2 (ACSS2) inhibitor with an IC50 of 0.6 µM. Ac-CoA Synthase Inhibitor1 inhibits the respiratory syncytial virus (RSV).
CAS:
508186-14-9
Molecular Weight:
410.51
Formula:
C20H18N4O2S2
Chemical Name:
1-[2,3-bis(thiophen-2-yl)quinoxalin-6-yl]-3-(2-methoxyethyl)urea
Smiles :
COCCNC(=O)NC1C=C2N=C(C(=NC2=CC=1)C1=CC=CS1)C1=CC=CS1
InChiKey:
CTPVNWVUAGMHEJ-UHFFFAOYSA-N
InChi :
InChI=1S/C20H18N4O2S2/c1-26-9-8-21-20(25)22-13-6-7-14-15(12-13)24-19(17-5-3-11-28-17)18(23-14)16-4-2-10-27-16/h2-7,10-12H,8-9H2,1H3,(H2,21,22,25)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Ac-CoA Synthase Inhibitor1 is a potent, reversible acetate-dependent acetyl-CoA synthetase 2 (ACSS2) inhibitor with an IC50 of 0.6 µM. Ac-CoA Synthase Inhibitor1 inhibits the respiratory syncytial virus (RSV).|Product information|CAS Number: 508186-14-9|Molecular Weight: 410.51|Formula: C20H18N4O2S2|Chemical Name: 1-[2,3-bis(thiophen-2-yl)quinoxalin-6-yl]-3-(2-methoxyethyl)urea|Smiles: COCCNC(=O)NC1C=C2N=C(C(=NC2=CC=1)C1=CC=CS1)C1=CC=CS1|InChiKey: CTPVNWVUAGMHEJ-UHFFFAOYSA-N|InChi: InChI=1S/C20H18N4O2S2/c1-26-9-8-21-20(25)22-13-6-7-14-15(12-13)24-19(17-5-3-11-28-17)18(23-14)16-4-2-10-27-16/h2-7,10-12H,8-9H2,1H3,(H2,21,22,25)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 31.25 mg/mL (76.Leniolisib manufacturer 12 mM; Need ultrasonic).FX-11 Description |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32955361 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Ac-CoA Synthase Inhibitor1 inhibits cellular [14C]acetate uptake into both lipids and histones with an IC50 of 5 µM. Ac-CoA Synthase Inhibitor1 inhibits the ability of HepG2 cells to incorporate [14C]acetate into lipids with IC50 of 6.8 µM. Ac-CoA Synthase Inhibitor1 inhibits HepG2 utilization of [14C]acetate for histone acetylation with IC50 of 5.5 µM.|Products are for research use only. Not for human use.|
