Product Name :
IDO1-IN-5
Description:
IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
CAS:
2166616-75-5
Molecular Weight:
396.45
Formula:
C23H25FN2O3
Chemical Name:
4-fluoro-N-[(1R)-1-[1-(oxane-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]ethyl]benzamide
Smiles :
C[C@@H](NC(=O)C1C=CC(F)=CC=1)C1C=C2CCN(C(=O)C3CCOCC3)C2=CC=1
InChiKey:
NUBWFWVVKLRSHS-OAHLLOKOSA-N
InChi :
InChI=1S/C23H25FN2O3/c1-15(25-22(27)16-2-5-20(24)6-3-16)18-4-7-21-19(14-18)8-11-26(21)23(28)17-9-12-29-13-10-17/h2-7,14-15,17H,8-13H2,1H3,(H,25,27)/t15-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.Sapienic acid custom synthesis
Additional information:
IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.AZD1390 Cell Cycle/DNA Damage |Product information|CAS Number: 2166616-75-5|Molecular Weight: 396.45|Formula: C23H25FN2O3|Chemical Name: 4-fluoro-N-[(1R)-1-[1-(oxane-4-carbonyl)-2,3-dihydro-1H-indol-5-yl]ethyl]benzamide|Smiles: C[C@@H](NC(=O)C1C=CC(F)=CC=1)C1C=C2CCN(C(=O)C3CCOCC3)C2=CC=1|InChiKey: NUBWFWVVKLRSHS-OAHLLOKOSA-N|InChi: InChI=1S/C23H25FN2O3/c1-15(25-22(27)16-2-5-20(24)6-3-16)18-4-7-21-19(14-18)8-11-26(21)23(28)17-9-12-29-13-10-17/h2-7,14-15,17H,8-13H2,1H3,(H,25,27)/t15-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 300 mg/mL (756.PMID:32568960 72 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|IDO1-IN-5 (up to 100 µM) shows no obvious agonism of aryl hydrocarbon receptor (AHR).|Products are for research use only. Not for human use.|
