39 45 113 55 57 29 69 5 12 28 16 14 37 56 30 42 20 30 41 73 72 26 82 28 6 32 27 63 31 52 56 37 3322 1 1002 1 2 0 -2 1 100 1 2 1 100 1 2 1 33 1 2 0 1 2 0 1 2 0 2 2 0 2 2 0 1 2 0 2 2 33 2 2 17 2 1 50 1 2 50 2 2 0 2 2 0 1 2 0 2 2 0 2 2 0 2 2 50 1 2 50 2 2 0 1 1 1 1 1 1 2 1 1 1 1 2 1 1 2 1 1 1 1 1 1 1 1 1 1 2 1 1 12 2 1002 1 1001202 1 1003 1 2 0 2 2 67 2 1 67 1 1 33 2 2 0 1 2 0 1 2 0 1 2 0 2 2201 195 107 108 296 234 49 18 65 46 19 63 18 72 472 1 2420 3 1 2(Continued)PLOS ONE | DOI:10.1371/journal.pone.0159193 July 14,10 /Gender-Differentiated Parental ControlTable

39 45 113 55 57 29 69 5 12 28 16 14 37 56 30 42 20 30 41 73 72 26 82 28 6 32 27 63 31 52 56 37 3322 1 1002 1 2 0 -2 1 100 1 2 1 100 1 2 1 33 1 2 0 1 2 0 1 2 0 2 2 0 2 2 0 1 2 0 2 2 33 2 2 17 2 1 50 1 2 50 2 2 0 2 2 0 1 2 0 2 2 0 2 2 0 2 2 50 1 2 50 2 2 0 1 1 1 1 1 1 2 1 1 1 1 2 1 1 2 1 1 1 1 1 1 1 1 1 1 2 1 1 12 2 1002 1 1001202 1 1003 1 2 0 2 2 67 2 1 67 1 1 33 2 2 0 1 2 0 1 2 0 1 2 0 2 2201 195 107 108 296 234 49 18 65 46 19 63 18 72 472 1 2420 3 1 2(Continued)PLOS ONE | DOI:10.1371/journal.pone.0159193 July 14,10 /Gender-Differentiated AZD-8055 biological activity Parental ControlTable 1. (Continued)Study Parenta AZD-8055MedChemExpress AZD-8055 Control typeb M M, F M, F M M, F M M M, F M C M, F M M M M, F M M M M M, F M, F M M M M, F M M, F M M M, F M M, F M M M M C M M M M M, F M M M M, F M + +, +, + +, +, +, +, +, +, +, +, + -, P +,-, P,H +, +, +, -,H +, +, +, +, -, H +, +, +, P +, +, +, +, +, +, +, P +, +, -, H Sample size 49 50 47 9 24 42 35 50 41 45 53 54 44 49 48 64 43 50 48 50 49 58 50 50 40 50 57 43 50 50 50 49 50 49 50 52 53 50 28 37 13 47 20 28 44 14 19 49 52 53 50 52 50 51 56 50 60 Age (in Ethnicityc Taskd years) 2.5 I 2.2 I 5.0 2.8 Mixed 6.1 1.0 NAC 1.5 Mixed 5.0 Mixed 3.5 Mixed 3.0 12.9 Mixed 1.3 Mixed 2.0 Mixed 4.0 NAC 2.0 Mixed 2.0 Mixed 6.0 C, WEC 0.9 SA 3.6 Mixed 12.3 NAC 4? 4.3 4.0 Mixed 11.0 AA 5.0 8.2 Mixed 3.6 Mixed 2.7 Mixed 1.2 Mixed 2.0 Mixed 3.1 WEC 4.0 3.9 NAC 5.8 SA 3.0 Mixed 3.1 Mixed 7.4 Mixed 1.2 Mixed 2.5 Mixed 5.2 C, NAC 1.0 Mixed 10.0 NAC 9.0 1.3 11.5 AA 8.4 5.3 SA D D N T F, T, M T D T T F, T, M T F D T M T D F T T T N D T T T F D D D D T T T T M D T F F F T T T T N T Sample normative Yes Yes Yes Yes Yes Yes Yes Yes Yes, No Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes No Yes No Yes Yes Yes Yes Yes Yes Yes Yes SESe Settingf Only verbal 2 4 4 4 4 4 1 1 4 4 4 3 1 4 2 4 4 3 1 4 3 2 4 4 4 4 4 4 4 4 4 4 3 4 2 4 4 1 L H H H H L L L L L H H H L L L H L H H H H L L H L L Mix L L L L L H L L L H L L L H L Mix L H H No No No No No No No No No No No No No Yes No No No No No No Yes No No No Yes No Yes No No No No No No No No No No Yes No No No No No No No No No Other moderatorsg 1 Feldman et al. 1986 [117] Feldman et al. 2003 [118] Fisher et al. 1993 [119] Frampton 2012 [120] Frankel et al. 1983 [121] Frodi et al. 1985 [122] Gaertner et al. 2008 [123] Gjerde et al. 1991 [124] Gordon 1983 [125] Gross et al. 2009 [126] Gunnoe et al. 1999 [127] Gustafsson et al. 2012 [128] Henderson 2007 [129] Hess et al. 1984 [130] Higgins 2008 [131] Holt 2008 [132] Huang et al. 2014 [133] Huber 2012 [134] Hughes et al. 1999 [135] Inoff-Germain et al. 1988 [136] Janssens et al. 1997 [137] Kagan et al. 1963 [138] Kalpidou et al. 1998 [139] Kapungu et al. 2006 [140] Kauffman 1985 [141] Kenny-Benson et al. 2005 [142] Kerig et al. 1993 [143] Kochanska 1995 [144] Kochanska et al. 2003 [145] Kochanska et al. 2009 [40] Kok et al. 2012 [146] Kuczynski 1984 [147] LaFreniere et al. 1992 [148] Laosa 1978 [149] Lengua et al. 2007 [150] Lengua et al. 2014 [151] Li and Lee 2013 [152] Lindsey et al. 2005 [153] Linver et al. 2002 [47] Liu et al. 2010 [154] Lloyd 2010 [155] Loeb 1980 [156] Longeway 1983 [157] Maccoby et al. 1984 [52] Mandara et al. 2012 [38] Margolin et al. 1975 [158] Martinez 1988 [159] 46 16 743 9 17 46 39 48 16 13 8 15 8 6 10 10 10 30 5 35 10 4 20 45 20 27 60 5 15 10 80 58 45 2 9 18 10 24 20 8 30 5 7 30 17 10 45 10 2 3 4 2 2 0 2 2 0 1 1 50 2 2 0 5 6 1 1 190120 -1.39 45 113 55 57 29 69 5 12 28 16 14 37 56 30 42 20 30 41 73 72 26 82 28 6 32 27 63 31 52 56 37 3322 1 1002 1 2 0 -2 1 100 1 2 1 100 1 2 1 33 1 2 0 1 2 0 1 2 0 2 2 0 2 2 0 1 2 0 2 2 33 2 2 17 2 1 50 1 2 50 2 2 0 2 2 0 1 2 0 2 2 0 2 2 0 2 2 50 1 2 50 2 2 0 1 1 1 1 1 1 2 1 1 1 1 2 1 1 2 1 1 1 1 1 1 1 1 1 1 2 1 1 12 2 1002 1 1001202 1 1003 1 2 0 2 2 67 2 1 67 1 1 33 2 2 0 1 2 0 1 2 0 1 2 0 2 2201 195 107 108 296 234 49 18 65 46 19 63 18 72 472 1 2420 3 1 2(Continued)PLOS ONE | DOI:10.1371/journal.pone.0159193 July 14,10 /Gender-Differentiated Parental ControlTable 1. (Continued)Study Parenta Control typeb M M, F M, F M M, F M M M, F M C M, F M M M M, F M M M M M, F M, F M M M M, F M M, F M M M, F M M, F M M M M C M M M M M, F M M M M, F M + +, +, + +, +, +, +, +, +, +, +, + -, P +,-, P,H +, +, +, -,H +, +, +, +, -, H +, +, +, P +, +, +, +, +, +, +, P +, +, -, H Sample size 49 50 47 9 24 42 35 50 41 45 53 54 44 49 48 64 43 50 48 50 49 58 50 50 40 50 57 43 50 50 50 49 50 49 50 52 53 50 28 37 13 47 20 28 44 14 19 49 52 53 50 52 50 51 56 50 60 Age (in Ethnicityc Taskd years) 2.5 I 2.2 I 5.0 2.8 Mixed 6.1 1.0 NAC 1.5 Mixed 5.0 Mixed 3.5 Mixed 3.0 12.9 Mixed 1.3 Mixed 2.0 Mixed 4.0 NAC 2.0 Mixed 2.0 Mixed 6.0 C, WEC 0.9 SA 3.6 Mixed 12.3 NAC 4? 4.3 4.0 Mixed 11.0 AA 5.0 8.2 Mixed 3.6 Mixed 2.7 Mixed 1.2 Mixed 2.0 Mixed 3.1 WEC 4.0 3.9 NAC 5.8 SA 3.0 Mixed 3.1 Mixed 7.4 Mixed 1.2 Mixed 2.5 Mixed 5.2 C, NAC 1.0 Mixed 10.0 NAC 9.0 1.3 11.5 AA 8.4 5.3 SA D D N T F, T, M T D T T F, T, M T F D T M T D F T T T N D T T T F D D D D T T T T M D T F F F T T T T N T Sample normative Yes Yes Yes Yes Yes Yes Yes Yes Yes, No Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes No Yes No Yes Yes Yes Yes Yes Yes Yes Yes SESe Settingf Only verbal 2 4 4 4 4 4 1 1 4 4 4 3 1 4 2 4 4 3 1 4 3 2 4 4 4 4 4 4 4 4 4 4 3 4 2 4 4 1 L H H H H L L L L L H H H L L L H L H H H H L L H L L Mix L L L L L H L L L H L L L H L Mix L H H No No No No No No No No No No No No No Yes No No No No No No Yes No No No Yes No Yes No No No No No No No No No No Yes No No No No No No No No No Other moderatorsg 1 Feldman et al. 1986 [117] Feldman et al. 2003 [118] Fisher et al. 1993 [119] Frampton 2012 [120] Frankel et al. 1983 [121] Frodi et al. 1985 [122] Gaertner et al. 2008 [123] Gjerde et al. 1991 [124] Gordon 1983 [125] Gross et al. 2009 [126] Gunnoe et al. 1999 [127] Gustafsson et al. 2012 [128] Henderson 2007 [129] Hess et al. 1984 [130] Higgins 2008 [131] Holt 2008 [132] Huang et al. 2014 [133] Huber 2012 [134] Hughes et al. 1999 [135] Inoff-Germain et al. 1988 [136] Janssens et al. 1997 [137] Kagan et al. 1963 [138] Kalpidou et al. 1998 [139] Kapungu et al. 2006 [140] Kauffman 1985 [141] Kenny-Benson et al. 2005 [142] Kerig et al. 1993 [143] Kochanska 1995 [144] Kochanska et al. 2003 [145] Kochanska et al. 2009 [40] Kok et al. 2012 [146] Kuczynski 1984 [147] LaFreniere et al. 1992 [148] Laosa 1978 [149] Lengua et al. 2007 [150] Lengua et al. 2014 [151] Li and Lee 2013 [152] Lindsey et al. 2005 [153] Linver et al. 2002 [47] Liu et al. 2010 [154] Lloyd 2010 [155] Loeb 1980 [156] Longeway 1983 [157] Maccoby et al. 1984 [52] Mandara et al. 2012 [38] Margolin et al. 1975 [158] Martinez 1988 [159] 46 16 743 9 17 46 39 48 16 13 8 15 8 6 10 10 10 30 5 35 10 4 20 45 20 27 60 5 15 10 80 58 45 2 9 18 10 24 20 8 30 5 7 30 17 10 45 10 2 3 4 2 2 0 2 2 0 1 1 50 2 2 0 5 6 1 1 190120 -1.