(B) CAT activity within the liver ofliver of ducks; (B) CAT activitythethe liver of ducks; (C) T-SOD activity DDR2 Biological Activity inside the liver of ducks; (D) the ducks; (C) T-SOD activity in in liver of ducks; (D) GSH content inside the liver of ducks; GSH content JNK1 Purity & Documentation material (F) H2 O2 of ducks; the liver of activity in MDA content in (F) H2O content material in (E) GSH-ST activity within the liver of ducks;in the livercontent in (E) GSH-ST ducks; (G)the liver of ducks;the liver2of ducks. the liver suggests p (G) MDA content inside the liver of ducks. Values imply the mean SEM, suggests p Values mean the mean SEM, of ducks; 0.01. 0.01.3.7. Expression of Molecules within the Nrf2-ARE Signaling pathway three.7. Expression of Molecules in the Nrf2-ARE Signaling Pathway response, suggesting the AFB1 administration is connected with cell antioxidant expression administration isparticipating within the Nrf2-ARE signaling pathway. As shownexAFB1 modifications in genes connected with cell antioxidant response, suggesting the in Figure 7A, compared with the T0 group, AFB1 administration decreased the As shown in pression modifications in genes participating inside the Nrf2-ARE signaling pathway.associated genes expression which includes with the 0.05), as well as enzymatic antioxidant program (CAT, genes Figure 7A, comparedNrf2 (p T0 group, AFB1 administration decreased the relatedSOD1, GPX1, and which includes Nrf2 (p phase as detoxifying enzymes (NQO1, method (CAT, SOD1, expression GST; p 0.05) and 0.05),(II) effectively as enzymatic antioxidantHO-1, GCLC, GCLM; p 0.05) in GST; + AFB1 group. As anticipated, in comparison together with the T0 HO-1, group, GPX1, along with the T0 p 0.05) and phase (II) detoxifying enzymes (NQO1, + AFB1 GCLC, curcumin supplementation considerably As expected, genes expression levels such as GCLM; p 0.05) within the T0 + AFB1 group. improved the in comparison with the T0 + AFB1 Nrf2, CAT, SOD1, GST, NQO1, HO-1, GCLC (p increased the genes expression levels ingroup, curcumin supplementation considerably 0.05) inside the T500 + AFB1 group; further there was an CAT, SOD1, GST, the GPX1 and GCLM 0.05) in 0.05). + addition, in cluding Nrf2, increasing trend inNQO1, HO-1, GCLC (p genes (p the T500 InAFB1 group; comparison with an T0 group, substantial GPX1 and GCLM genes (p 0.05). Furthermore, additional there wasthe increasingatrend in theincrease in genes expressionof Nrf2, SOD1 and NQO1 (p 0.05) as well as a T0 group, a important increase in expression of CAT, GST, SOD1 in comparison with thegenerally rising trend of genegenes expression of Nrf2, HO-1, GCLC, GPX1, 0.05) and also a 0.05) in growing trend of gene expression and NQO1 (p and GCLM (p typically the T0 + AFB1 group have been observed. of CAT, GST,HO-1, GCLC, GPX1, and GCLM (p 0.05) in the T0 + AFB1 group had been observed.Foods 2021, ten, 3086 Foods 2021, ten, x FOR PEER REVIEW9 of 17 11 ofFigure 7. Gene pathway in liver of ducks exposed to in liver of ducks exposed to AFB1 at 12 Figure 7. Gene expression in Nrf2 signalingexpression in Nrf2 signaling pathwayAFB1 at 12 h. (A) Nrf2 gene expression inh. (A) Nrf2 gene expression liver liver of ducks; (B) CAT gene expression in the of ducks; (D) (C) the liver of ducks; (B) CAT gene expression in thein the of ducks; (C) SOD1 gene expression within the liverliver of ducks; GPxSOD1 gene expression in the liver of ducks; (D) GPx gene expression in the liver of ducks; (E) GST gene gene expression within the liver of ducks; (E) GST gene expression inside the liver of ducks; (F) NQO-1 gene expression inside the liver expression within the liver of ducks; (F) NQO-1 gene e
